Choice of cyclodextrin for cellular cholesterol depletion for vascular endothelial cell lipid raft studies: cell membrane alterations, cytoskeletal reorganization and cytotoxicity.

Hinzey, Adam H; Kline, Michelle A; Kotha, Sainath R; Sliman, Sean M; Butler, Elizabeth S O'Connor; Shelton, Andrew B; Gurney, Travis R; Parinandi, Narasimham L

Hinzey, Adam H; Kline, Michelle A; Kotha, Sainath R; Sliman, Sean M; Butler, Elizabeth S O'Connor; Shelton, Andrew B; Gurney, Travis R; Parinandi, Narasimham L.

Affiliation

Hinzey AH; Lipid Signaling, Lipidomics, and Vasculotoxicity Laboratory, Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University College of Medicine, Columbus, OH 43210, USA.

Indian J Biochem Biophys ; 49(5): 329-41, 2012 Oct.

Article in En | MEDLINE | ID: mdl-23259319

Subject(s)

Cholesterol/metabolism; Cyclodextrins/pharmacology; Cyclodextrins/toxicity; Cytoskeleton/physiology; Endothelial Cells/physiology; Membrane Fluidity/physiology; Membrane Microdomains/physiology; Animals; Cattle; Cell Survival/drug effects; Cells, Cultured; Cholesterol/isolation & purification; Cytoskeleton/drug effects; Dose-Response Relationship, Drug; Endothelial Cells/cytology; Endothelial Cells/drug effects; Membrane Fluidity/drug effects; Membrane Microdomains/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Cytoskeleton / Cholesterol / Cyclodextrins / Membrane Microdomains / Endothelial Cells / Membrane Fluidity Limits: Animals Language: En Journal: Indian J Biochem Biophys Year: 2012 Type: Article Affiliation country: United States

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