Platelet ITAM signaling is critical for vascular integrity in inflammation.

Boulaftali, Yacine; Hess, Paul R; Getz, Todd M; Cholka, Agnieszka; Stolla, Moritz; Mackman, Nigel; Owens, A Phillip; Ware, Jerry; Kahn, Mark L; Bergmeier, Wolfgang

Boulaftali, Yacine; Hess, Paul R; Getz, Todd M; Cholka, Agnieszka; Stolla, Moritz; Mackman, Nigel; Owens, A Phillip; Ware, Jerry; Kahn, Mark L; Bergmeier, Wolfgang.

Affiliation

Boulaftali Y; McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

J Clin Invest ; 123(2): 908-16, 2013 Feb.

Article in En | MEDLINE | ID: mdl-23348738

Subject(s)

Blood Platelets/physiology; Blood Vessels/physiopathology; Inflammation/blood; Inflammation/physiopathology; Adaptor Proteins, Signal Transducing/antagonists & inhibitors; Adaptor Proteins, Signal Transducing/blood; Adoptive Transfer; Animals; Hemostasis; Lectins, C-Type/deficiency; Lectins, C-Type/genetics; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Phosphoproteins/antagonists & inhibitors; Phosphoproteins/blood; Platelet Membrane Glycoproteins/antagonists & inhibitors; Platelet Membrane Glycoproteins/physiology; Receptors, G-Protein-Coupled/blood; Receptors, G-Protein-Coupled/physiology; Receptors, Thrombin/blood; Receptors, Thrombin/deficiency; Receptors, Thrombin/genetics; Signal Transduction; Thrombocytopenia/blood; Thrombocytopenia/physiopathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Platelets / Blood Vessels / Inflammation Type of study: Guideline Limits: Animals Language: En Journal: J Clin Invest Year: 2013 Type: Article Affiliation country: United States

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