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Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites.
Kimura, Taeko; Tsutsumi, Koji; Taoka, Masato; Saito, Taro; Masuda-Suzukake, Masami; Ishiguro, Koichi; Plattner, Florian; Uchida, Takafumi; Isobe, Toshiaki; Hasegawa, Masato; Hisanaga, Shin-Ichi.
Affiliation
  • Kimura T; Laboratory of Molecular Neuroscience, Department of Biological Sciences, Tokyo Metropolitan University, Hachioji, Tokyo 192-0397, Japan.
  • Tsutsumi K; Laboratory of Molecular Neuroscience, Department of Biological Sciences, Tokyo Metropolitan University, Hachioji, Tokyo 192-0397, Japan.
  • Taoka M; Department of Chemistry, Tokyo Metropolitan University, Hachioji, Tokyo 192-0397, Japan.
  • Saito T; Laboratory of Molecular Neuroscience, Department of Biological Sciences, Tokyo Metropolitan University, Hachioji, Tokyo 192-0397, Japan.
  • Masuda-Suzukake M; Tokyo Metropolitan Institute of Medical Science, Setagaya, Tokyo 156-8506, Japan.
  • Ishiguro K; Mitsubishi Kagaku Institute of Life Science, Machida, Tokyo 194-8511, Japan.
  • Plattner F; University of Texas Southwestern Medical Center, Dallas, Texas 75390-9070.
  • Uchida T; Department of Molecular Cell Biology, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi 981-8555, Japan.
  • Isobe T; Department of Chemistry, Tokyo Metropolitan University, Hachioji, Tokyo 192-0397, Japan.
  • Hasegawa M; Tokyo Metropolitan Institute of Medical Science, Setagaya, Tokyo 156-8506, Japan.
  • Hisanaga SI; Laboratory of Molecular Neuroscience, Department of Biological Sciences, Tokyo Metropolitan University, Hachioji, Tokyo 192-0397, Japan. Electronic address: hisanaga-shinichi@tmu.ac.jp.
J Biol Chem ; 288(11): 7968-7977, 2013 Mar 15.
Article in En | MEDLINE | ID: mdl-23362255
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Peptidylprolyl Isomerase / Cyclin-Dependent Kinase 5 / Alzheimer Disease / Mutation Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2013 Type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Peptidylprolyl Isomerase / Cyclin-Dependent Kinase 5 / Alzheimer Disease / Mutation Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2013 Type: Article Affiliation country: Japan