Accuracy and precision of transcutaneous bilirubinometry in postdischarge Asian neonates.
Eur J Pediatr
; 172(6): 781-6, 2013 Jun.
Article
in En
| MEDLINE
| ID: mdl-23397326
ABSTRACT
UNLABELLED A prospective cross-sectional study was conducted in a tertiary care center to determine the accuracy of transcutaneous bilirubin measurements (TcB) measured by the Konica Minolta JM-103™ meter compared to total serum bilirubin (TSB) in Asian infants aged 5-14 days. There were 405 late-preterm and term infants involved, and 455 paired samples were obtained by venepuncture and analyzed for bilirubin levels. TcB measurements were performed using the average of three measurements (TcB3) and a single measurement (TcB1) method. The overall correlation between TSB and the TcB was 0.80 (p ≤ 0.001) for TcB3 and 0.76 (p ≤ 0.001) for TcB1, respectively. The mean (SD) difference between TcB3 and TSB was -17.6 (29.5) µmol/L (median, -17.0; interquartile range (IQR), -39.1 to 1.7) and between TcB1 and TSB was -20.7 (32.3) µmol/L (median, -20.4; IQR, -42.5 to 1.7). The mean difference (SD) between the TcB3 and TSB in the low-risk (TSB < 170 µmol/L), intermediate-risk (TSB 170-254 µmol/L), and high-risk (TSB ≥ 255 µmol/L) groups was -2.8 (27.2), -13.4 (27.0), and -33.4 (29.1) µmol/L, respectively. To detect a TSB level of ≥255 µmol/L, using the TcB cutoff level of 204 µmol/L provides a sensitivity of 96 % with a specificity of 58 %. CONCLUSION:
The TcB meter using a specific cutoff level can be reliably used as a screening tool for jaundice detection in older, postdischarge neonates, including the Asian population. Lower cutoff values can be set to capture all infants who merit closer surveillance, potential investigation, and treatment with higher accompanying screening costs.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bilirubin
/
Asian People
/
Optical Devices
/
Jaundice, Neonatal
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
/
Newborn
Country/Region as subject:
Asia
Language:
En
Journal:
Eur J Pediatr
Year:
2013
Type:
Article
Affiliation country:
Thailand