Viral escape from neutralizing antibodies in early subtype A HIV-1 infection drives an increase in autologous neutralization breadth.

Murphy, Megan K; Yue, Ling; Pan, Ruimin; Boliar, Saikat; Sethi, Anurag; Tian, Jianhui; Pfafferot, Katja; Karita, Etienne; Allen, Susan A; Cormier, Emmanuel; Goepfert, Paul A; Borrow, Persephone; Robinson, James E; Gnanakaran, S; Hunter, Eric; Kong, Xiang-Peng; Derdeyn, Cynthia A

Murphy, Megan K; Yue, Ling; Pan, Ruimin; Boliar, Saikat; Sethi, Anurag; Tian, Jianhui; Pfafferot, Katja; Karita, Etienne; Allen, Susan A; Cormier, Emmanuel; Goepfert, Paul A; Borrow, Persephone; Robinson, James E; Gnanakaran, S; Hunter, Eric; Kong, Xiang-Peng; Derdeyn, Cynthia A.

Affiliation

Murphy MK; Immunology and Molecular Pathogenesis Graduate Program, Emory University, Atlanta, Georgia, United States of America.

PLoS Pathog ; 9(2): e1003173, 2013 Feb.

Article in En | MEDLINE | ID: mdl-23468623

Subject(s)

Antibodies, Neutralizing/immunology; Antibodies, Viral/immunology; HIV Infections/immunology; HIV-1/immunology; Immune Evasion/immunology; Amino Acid Sequence; Antibodies, Neutralizing/chemistry; Cross Reactions/immunology; Female; HIV Infections/virology; HIV Seropositivity/immunology; HIV Seropositivity/virology; Humans; Immunoglobulin Heavy Chains/immunology; Immunoglobulin Light Chains/immunology; Male; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Alignment

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / Antibodies, Neutralizing / Immune Evasion / Antibodies, Viral Limits: Female / Humans / Male Language: En Journal: PLoS Pathog Year: 2013 Type: Article Affiliation country: United States

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