Human equilibrative nucleoside transporter 1 and Notch3 can predict gemcitabine effects in patients with unresectable pancreatic cancer.

Eto, K; Kawakami, H; Kuwatani, M; Kudo, T; Abe, Y; Kawahata, S; Takasawa, A; Fukuoka, M; Matsuno, Y; Asaka, M; Sakamoto, N

Eto, K; Kawakami, H; Kuwatani, M; Kudo, T; Abe, Y; Kawahata, S; Takasawa, A; Fukuoka, M; Matsuno, Y; Asaka, M; Sakamoto, N.

Affiliation

Eto K; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan.

Br J Cancer ; 108(7): 1488-94, 2013 Apr 16.

Article in En | MEDLINE | ID: mdl-23492684

Subject(s)

Antimetabolites, Antineoplastic/therapeutic use; Carcinoma, Pancreatic Ductal/drug therapy; Deoxycytidine/analogs & derivatives; Equilibrative Nucleoside Transporter 1/metabolism; Pancreatic Neoplasms/drug therapy; Receptors, Notch/metabolism; Adult; Aged; Aged, 80 and over; Carcinoma, Pancreatic Ductal/genetics; Carcinoma, Pancreatic Ductal/metabolism; Deoxycytidine/therapeutic use; Equilibrative Nucleoside Transporter 1/genetics; Female; Humans; Male; Middle Aged; Pancreatic Neoplasms/genetics; Pancreatic Neoplasms/metabolism; RNA, Messenger/biosynthesis; RNA, Messenger/genetics; Receptor, Notch3; Receptors, Notch/genetics; Retrospective Studies; Gemcitabine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Carcinoma, Pancreatic Ductal / Equilibrative Nucleoside Transporter 1 / Deoxycytidine / Receptors, Notch / Antimetabolites, Antineoplastic Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Br J Cancer Year: 2013 Type: Article Affiliation country: Japan

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