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Artifacts in polarization-sensitive optical coherence tomography caused by polarization mode dispersion.
Villiger, Martin; Zhang, Ellen Ziyi; Nadkarni, Seemantini; Oh, Wang-Yuhl; Bouma, Brett E; Vakoc, Benjamin J.
Affiliation
  • Villiger M; Wellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts 02114, USA. mvilliger@partners.org
Opt Lett ; 38(6): 923-5, 2013 Mar 15.
Article in En | MEDLINE | ID: mdl-23503261
ABSTRACT
Polarization mode dispersion (PMD) severely degrades images of biological tissue measured with polarization-sensitive optical coherence tomography. It adds a bias to the local retardation value that can be spatially confined, resulting in regions of seemingly high sample birefringence that are purely artificial. Here, we demonstrate and analyze this effect, both experimentally and with numerical simulations, and show that artifacts can be avoided by limiting the system PMD to less than the system axial resolution. Even then, spatial averaging over a dimension larger than that characteristic of speckle is required to remove a PMD-induced bias of the local retardation values.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Image Enhancement / Artifacts / Tomography, Optical Coherence Type of study: Diagnostic_studies Language: En Journal: Opt Lett Year: 2013 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Image Enhancement / Artifacts / Tomography, Optical Coherence Type of study: Diagnostic_studies Language: En Journal: Opt Lett Year: 2013 Type: Article Affiliation country: United States