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PEG as a spacer arm markedly increases the immunogenicity of meningococcal group Y polysaccharide conjugate vaccine.
Huang, Qingrui; Li, Dongxia; Kang, Aijun; An, Wenqi; Fan, Bei; Ma, Xiaowei; Ma, Guanghui; Su, Zhiguo; Hu, Tao.
Affiliation
  • Huang Q; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100190, China.
  • Li D; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
  • Kang A; Department of Laboratory Animal Science, Peking University Health Science Center, Beijing 100191, China.
  • An W; Hualan Biological Engineering, Inc., Xinxiang 453003, Henan Province, China.
  • Fan B; Hualan Biological Engineering, Inc., Xinxiang 453003, Henan Province, China.
  • Ma X; Hualan Biological Engineering, Inc., Xinxiang 453003, Henan Province, China.
  • Ma G; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
  • Su Z; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
  • Hu T; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China. Electronic address: thu@home.ipe.ac.cn.
J Control Release ; 172(1): 382-389, 2013 Nov 28.
Article in En | MEDLINE | ID: mdl-23511718
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Polysaccharides, Bacterial / Vaccines, Conjugate / Meningitis, Meningococcal / Neisseria meningitidis Limits: Animals / Female / Humans Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2013 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Polysaccharides, Bacterial / Vaccines, Conjugate / Meningitis, Meningococcal / Neisseria meningitidis Limits: Animals / Female / Humans Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2013 Type: Article Affiliation country: China