Early effects of high-fat diet on neurovascular function and focal ischemic brain injury.

Li, Weiguo; Prakash, Roshini; Chawla, Dhruv; Du, Wenting; Didion, Sean P; Filosa, Jessica A; Zhang, Quanguang; Brann, Darrell W; Lima, Victor V; Tostes, Rita C; Ergul, Adviye

Li, Weiguo; Prakash, Roshini; Chawla, Dhruv; Du, Wenting; Didion, Sean P; Filosa, Jessica A; Zhang, Quanguang; Brann, Darrell W; Lima, Victor V; Tostes, Rita C; Ergul, Adviye.

Affiliation

Li W; Charlie Norwood Department of Veterans Affairs Medical Center, Augusta, GA, USA.

Am J Physiol Regul Integr Comp Physiol ; 304(11): R1001-8, 2013 Jun 01.

Article in En | MEDLINE | ID: mdl-23576615

Subject(s)

Brain Ischemia/etiology; Brain Ischemia/physiopathology; Cerebrovascular Circulation/physiology; Diet, High-Fat/adverse effects; Animals; Arterioles/physiology; Basilar Artery/pathology; Brain/pathology; Cerebral Hemorrhage/physiopathology; Cerebrovascular Disorders/physiopathology; Cholesterol/blood; Hyperemia/physiopathology; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery/pathology; Infarction, Middle Cerebral Artery/physiopathology; Insulin/blood; Male; Microscopy, Video; Muscle Contraction/physiology; N-Acetylglucosaminyltransferases/metabolism; Obesity/physiopathology; Rats; Rats, Wistar; Triglycerides/blood

Key words

cerebral ischemia; hemorrhagic transformation; high-fat diet; neurovascular coupling; vascular dysfunction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Ischemia / Cerebrovascular Circulation / Diet, High-Fat Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Am J Physiol Regul Integr Comp Physiol Journal subject: FISIOLOGIA Year: 2013 Type: Article Affiliation country: United States

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