The Sterol-C7 desaturase from the ciliate Tetrahymena thermophila is a Rieske Oxygenase, which is highly conserved in animals.

Najle, Sebastián R; Nusblat, Alejandro D; Nudel, Clara B; Uttaro, Antonio D

Najle, Sebastián R; Nusblat, Alejandro D; Nudel, Clara B; Uttaro, Antonio D.

Affiliation

Najle SR; Instituto de Biología Molecular y Celular de Rosario, CONICET, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Argentina.

Mol Biol Evol ; 30(7): 1630-43, 2013 Jul.

Article in En | MEDLINE | ID: mdl-23603937

Subject(s)

Cholesterol/metabolism; Conserved Sequence; Fatty Acid Desaturases/metabolism; Oxidation-Reduction; Tetrahymena thermophila/enzymology; Animals; Cholestenes/metabolism; Cholesterol/chemistry; Cytochromes b5/metabolism; Ecdysteroids/biosynthesis; Fatty Acid Desaturases/chemistry; Fatty Acid Desaturases/classification; Phytosterols/metabolism; Sterols/metabolism

Key words

RNA interference; Rieske oxygenase; ciliates; phylogeny; sterol desaturase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidation-Reduction / Cholesterol / Tetrahymena thermophila / Conserved Sequence / Fatty Acid Desaturases Limits: Animals Language: En Journal: Mol Biol Evol Journal subject: BIOLOGIA MOLECULAR Year: 2013 Type: Article Affiliation country: Argentina

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