Monoclonal antibodies combined with adenovirus-vectored interferon significantly extend the treatment window in Ebola virus-infected guinea pigs.

Qiu, Xiangguo; Wong, Gary; Fernando, Lisa; Ennis, Jane; Turner, Jeffrey D; Alimonti, Judie B; Yao, Xiaojian; Kobinger, Gary P

Qiu, Xiangguo; Wong, Gary; Fernando, Lisa; Ennis, Jane; Turner, Jeffrey D; Alimonti, Judie B; Yao, Xiaojian; Kobinger, Gary P.

Affiliation

Qiu X; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada. xiangguo_qiu@phac-aspc.ga.ca

J Virol ; 87(13): 7754-7, 2013 Jul.

Article in En | MEDLINE | ID: mdl-23616649

Subject(s)

Antibodies, Monoclonal/immunology; Antibodies, Monoclonal/therapeutic use; Ebolavirus/immunology; Hemorrhagic Fever, Ebola/drug therapy; Hemorrhagic Fever, Ebola/immunology; Interferon-alpha/therapeutic use; Adenoviridae; Animals; Genetic Vectors/genetics; Guinea Pigs; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon-alpha / Hemorrhagic Fever, Ebola / Ebolavirus / Antibodies, Monoclonal Limits: Animals Language: En Journal: J Virol Year: 2013 Type: Article Affiliation country: Canada

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