Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages.

Stott, Simon R W; Metzakopian, Emmanouil; Lin, Wei; Kaestner, Klaus H; Hen, Rene; Ang, Siew-Lan

Stott, Simon R W; Metzakopian, Emmanouil; Lin, Wei; Kaestner, Klaus H; Hen, Rene; Ang, Siew-Lan.

Affiliation

Stott SR; Developmental Neurobiology, Medical Research Council National Institute for Medical Research, London NW7 1AA, United Kingdom.

J Neurosci ; 33(18): 8022-34, 2013 May 01.

Article in En | MEDLINE | ID: mdl-23637192

Subject(s)

Dopaminergic Neurons/physiology; Gene Expression Regulation, Developmental/genetics; Hepatocyte Nuclear Factor 3-alpha/metabolism; Hepatocyte Nuclear Factor 3-beta/metabolism; Mesencephalon/cytology; Analysis of Variance; Animals; Bacterial Proteins/metabolism; Cell Death/genetics; Cell Differentiation/genetics; Cell Movement/genetics; Cell Size; Chromatin Immunoprecipitation; Dopamine Plasma Membrane Transport Proteins/genetics; Embryo, Mammalian; Gait/genetics; Hepatocyte Nuclear Factor 3-alpha/deficiency; Hepatocyte Nuclear Factor 3-beta/deficiency; In Situ Nick-End Labeling; Luminescent Proteins/metabolism; Mesencephalon/embryology; Mice; Mice, Transgenic; Mutation/genetics; Nerve Fibers/physiology; Nerve Tissue Proteins/metabolism; Protein Binding/genetics; Proteins/genetics; Proteins/metabolism; RNA, Untranslated; Tyrosine 3-Monooxygenase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mesencephalon / Gene Expression Regulation, Developmental / Hepatocyte Nuclear Factor 3-alpha / Hepatocyte Nuclear Factor 3-beta / Dopaminergic Neurons Limits: Animals Language: En Journal: J Neurosci Year: 2013 Type: Article Affiliation country: United kingdom

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