Perirenal fat invasion on renal cell carcinoma: evaluation with multidetector computed tomography-multivariate analysis.
J Comput Assist Tomogr
; 37(3): 450-7, 2013.
Article
in En
| MEDLINE
| ID: mdl-23674020
ABSTRACT
OBJECTIVE:
The objective of this study was to assess the accuracy of multidetector computed tomography (CT) in diagnosing perinephric (PN) and/or renal sinus (RS) fat invasion in patients with renal cell carcinoma (RCC), with reference to the CT findings predictive for the diagnosis of invasion.METHODS:
This was a retrospective study of 48 RCCs. Examinations were performed on a 16-row CT scanner, including unenhanced and 3-phase contrast-enhanced CT scanning. Unenhanced transverse images and multiplanar reformations of each contrast-enhanced CT phase were evaluated. The predictive value of CT findings in diagnosing PN and/or RS fat invasion was determined using multivariate logistic regression analysis.RESULTS:
The CT findings that were most predictive for the diagnosis of PN fat invasion were the presence of contrast-enhancing nodules in the PN fat and tumoral margins. Invasion of the pelvicaliceal system was the most significant predictor in the diagnosis of RS fat invasion.CONCLUSIONS:
Multidetector CT provides satisfactory results in detecting PN and/or RS fat invasion in RCC.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Carcinoma, Renal Cell
/
Adipose Tissue
/
Multidetector Computed Tomography
/
Kidney Neoplasms
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Comput Assist Tomogr
Year:
2013
Type:
Article
Affiliation country:
Greece