The pre-synaptic Munc13-1 binds alcohol and modulates alcohol self-administration in Drosophila.

Das, Joydip; Xu, Shiyu; Pany, Satyabrata; Guillory, Ashley; Shah, Vrutant; Roman, Gregg W

Das, Joydip; Xu, Shiyu; Pany, Satyabrata; Guillory, Ashley; Shah, Vrutant; Roman, Gregg W.

Affiliation

Das J; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas 77204, USA. jdas@uh.edu

J Neurochem ; 126(6): 715-26, 2013 Sep.

Article in En | MEDLINE | ID: mdl-23692447

Subject(s)

Alcohols/metabolism; Caenorhabditis elegans Proteins/genetics; Drosophila melanogaster/physiology; Amino Acid Sequence; Animals; Behavior, Animal/drug effects; Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans Proteins/physiology; Carrier Proteins; Central Nervous System Depressants/pharmacology; Circular Dichroism; Escherichia coli/metabolism; Ethanol/pharmacology; Fluorescence; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation/genetics; Mutation/physiology; Photochemistry; Self Administration; Spectrometry, Fluorescence

Key words

Drosophila; alcohol; mass spectrometry; pre-synaptic; protein kinase C

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Caenorhabditis elegans Proteins / Drosophila melanogaster / Alcohols Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Neurochem Year: 2013 Type: Article Affiliation country: United States

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