MicroRNA-26 was decreased in rat cardiac hypertrophy model and may be a promising therapeutic target.

Zhang, Zhen-hui; Li, Jiao; Liu, Ben-rong; Luo, Cheng-feng; Dong, Qi; Zhao, Lu-ning; Zhong, Yun; Chen, Wei-yan; Chen, Min-sheng; Liu, Shi-ming

Zhang, Zhen-hui; Li, Jiao; Liu, Ben-rong; Luo, Cheng-feng; Dong, Qi; Zhao, Lu-ning; Zhong, Yun; Chen, Wei-yan; Chen, Min-sheng; Liu, Shi-ming.

Affiliation

Zhang ZH; *Intensive Care Unit; and Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; Guangzhou Institute of Cardiovascular Disease, Guangzhou, China; §Department of Physiology, Guangzhou Medical University, Guangzhou, China; and ¶Experimental Medicine Research Center, Guangzhou Medical University, Guangzhou, China.

J Cardiovasc Pharmacol ; 62(3): 312-9, 2013 Sep.

Article in En | MEDLINE | ID: mdl-23719092

Subject(s)

Cardiomegaly/metabolism; Disease Models, Animal; Down-Regulation; MicroRNAs/metabolism; Myocardium/metabolism; Animals; Animals, Newborn; Cardiomegaly/genetics; Cardiomegaly/pathology; Cardiomegaly/therapy; Cells, Cultured; Genetic Therapy; Glycogen Synthase Kinase 3/biosynthesis; Glycogen Synthase Kinase 3/genetics; Glycogen Synthase Kinase 3/metabolism; HEK293 Cells; Humans; Male; MicroRNAs/antagonists & inhibitors; Molecular Targeted Therapy; Myocardium/pathology; Myocytes, Cardiac/cytology; Myocytes, Cardiac/metabolism; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Down-Regulation / Cardiomegaly / MicroRNAs / Disease Models, Animal / Myocardium Type of study: Clinical_trials Limits: Animals / Humans / Male Language: En Journal: J Cardiovasc Pharmacol Year: 2013 Type: Article Affiliation country: China

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