pH-Switchable macroscopic assembly through host-guest inclusion.
Macromol Rapid Commun
; 34(14): 1174-80, 2013 Jul 25.
Article
in En
| MEDLINE
| ID: mdl-23744745
ABSTRACT
A novel pH-switchable macroscopic assembly is reported using alginate-based hydrogels functionalized with host (α-cyclodextrin, αCD) and guest (diethylenetriamine, DETA) moieties. Since the interaction of αCD and DETA is pH sensitive, the host hydrogel and guest hydrogel could adhere together when the pH is 11.5 and separate when the pH is 7.0. Furthermore, this pH-controlled adhesion and dissociation shows a good reversibility. The host and guest polymers have good biocompatibility; therefore, this pH-sensitive macroscopic assembly shows great potential in biotechnological and biomedical applications.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Polyamines
/
Hydrogels
/
Alpha-Cyclodextrins
/
Alginates
Language:
En
Journal:
Macromol Rapid Commun
Year:
2013
Type:
Article
Affiliation country:
China