Hoxa9 and Flt3 signaling synergistically regulate an early checkpoint in lymphopoiesis.

Gwin, Kimberly A; Shapiro, Mariya B; Dolence, Joseph J; Huang, Zhixin L; Medina, Kay L

Gwin, Kimberly A; Shapiro, Mariya B; Dolence, Joseph J; Huang, Zhixin L; Medina, Kay L.

Affiliation

Gwin KA; Department of Immunology, Mayo Clinic, Rochester, MN 55905, USA.

J Immunol ; 191(2): 745-54, 2013 Jul 15.

Article in En | MEDLINE | ID: mdl-23772038

Subject(s)

Homeodomain Proteins/metabolism; Lymphoid Progenitor Cells/cytology; Lymphopoiesis; fms-Like Tyrosine Kinase 3/metabolism; Animals; Antigens, CD/metabolism; Antigens, CD34/metabolism; B-Lymphocytes/immunology; Bone Marrow Cells/cytology; Bone Marrow Cells/metabolism; Cell Differentiation; Cell Lineage/immunology; Dendritic Cells/immunology; Granulocyte-Macrophage Progenitor Cells/cytology; Homeodomain Proteins/genetics; Killer Cells, Natural/immunology; Lymphocyte Count; Lymphoid Progenitor Cells/immunology; Lymphopoiesis/genetics; Membrane Proteins/genetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Membrane Glycoprotein IIb/metabolism; Receptors, Cell Surface/metabolism; Signal Transduction/immunology; Signaling Lymphocytic Activation Molecule Family Member 1; Transcription, Genetic; fms-Like Tyrosine Kinase 3/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Homeodomain Proteins / Lymphopoiesis / Fms-Like Tyrosine Kinase 3 / Lymphoid Progenitor Cells Limits: Animals Language: En Journal: J Immunol Year: 2013 Type: Article Affiliation country: United States

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