Daily acyclovir to decrease herpes simplex virus type 2 (HSV-2) transmission from HSV-2/HIV-1 coinfected persons: a randomized controlled trial.

Mujugira, Andrew; Magaret, Amalia S; Celum, Connie; Baeten, Jared M; Lingappa, Jairam R; Morrow, Rhoda Ashley; Fife, Kenneth H; Delany-Moretlwe, Sinead; de Bruyn, Guy; Bukusi, Elizabeth A; Karita, Etienne; Kapiga, Saidi; Corey, Lawrence; Wald, Anna

Mujugira, Andrew; Magaret, Amalia S; Celum, Connie; Baeten, Jared M; Lingappa, Jairam R; Morrow, Rhoda Ashley; Fife, Kenneth H; Delany-Moretlwe, Sinead; de Bruyn, Guy; Bukusi, Elizabeth A; Karita, Etienne; Kapiga, Saidi; Corey, Lawrence; Wald, Anna.

Affiliation

Mujugira A; Department of Global Health.

J Infect Dis ; 208(9): 1366-74, 2013 Nov 01.

Article in En | MEDLINE | ID: mdl-23901094

Subject(s)

Acyclovir/administration & dosage; Antiviral Agents/administration & dosage; Coinfection/drug therapy; HIV Infections/drug therapy; HIV-1; Herpes Genitalis/prevention & control; Herpesvirus 2, Human/drug effects; Adult; Coinfection/epidemiology; Coinfection/virology; Drug Administration Schedule; Female; HIV Infections/epidemiology; HIV Infections/virology; Herpes Genitalis/epidemiology; Herpes Genitalis/transmission; Humans; Incidence; Kaplan-Meier Estimate; Male; Multivariate Analysis; Proportional Hazards Models; Treatment Outcome

Key words

Africa; HIV-1; HSV-2; acyclovir; serodiscordant couples; transmission

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Acyclovir / Herpes Genitalis / HIV Infections / HIV-1 / Herpesvirus 2, Human / Coinfection Type of study: Clinical_trials / Incidence_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: J Infect Dis Year: 2013 Type: Article

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