Antinociceptive effect of Mirabilis jalapa on acute and chronic pain models in mice.

Walker, Cristiani I B; Trevisan, Gabriela; Rossato, Mateus F; Silva, Cássia R; Pinheiro, Franciele V; Franciscato, Carina; Tatsch, Etiane; Moretto, Maria B; Silva, Morgana D; Manfron, Melânia P; Noal Moresco, Rafael; Santos, Adair R S; Pereira, Maria E; Ferreira, Juliano

Walker, Cristiani I B; Trevisan, Gabriela; Rossato, Mateus F; Silva, Cássia R; Pinheiro, Franciele V; Franciscato, Carina; Tatsch, Etiane; Moretto, Maria B; Silva, Morgana D; Manfron, Melânia P; Noal Moresco, Rafael; Santos, Adair R S; Pereira, Maria E; Ferreira, Juliano.

Affiliation

Walker CI; Departamento de Saúde, Curso de Farmácia, Universidade Federal de Sergipe, SE, Brazil; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil. Electronic address: bandewalk@hotmail.com.

J Ethnopharmacol ; 149(3): 685-93, 2013 Oct 07.

Article in En | MEDLINE | ID: mdl-23906783

Subject(s)

Acute Pain/drug therapy; Analgesics/therapeutic use; Chronic Pain/drug therapy; Plant Extracts/therapeutic use; Acetylcholinesterase/metabolism; Acute Pain/enzymology; Acute Pain/immunology; Analgesics/isolation & purification; Analgesics/toxicity; Animals; Arthritis, Experimental/drug therapy; Arthritis, Experimental/enzymology; Arthritis, Experimental/immunology; Chronic Pain/enzymology; Chronic Pain/immunology; Hyperalgesia/drug therapy; Hyperalgesia/enzymology; Hyperalgesia/immunology; Interleukin-1beta/immunology; Male; Mice; Pain Measurement; Pain, Postoperative/drug therapy; Pain, Postoperative/enzymology; Pain, Postoperative/immunology; Plant Extracts/isolation & purification; Plant Extracts/toxicity; Plant Leaves/chemistry; Sciatic Neuropathy/drug therapy; Sciatic Neuropathy/enzymology; Sciatic Neuropathy/immunology

Key words

AChE; ALT; AST; Acetylcholinesterase; Antinociceptive; CFA; Eta; IL-1ß; M. jalapa; Mirabilis jalapa; Muscarinic; Nicotinic; Nyctaginaceae; Pain; alanine aminotransferase; aspartate aminotransferase; complete Freund's Adjuvant; i.p.; interleukin-1ß; intraperitoneal administration; oral administration; p.o.; s.c.; subcutaneous route; the leaf ethyl acetate fraction from Mirabilis jalapa

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Acute Pain / Chronic Pain / Analgesics Limits: Animals Language: En Journal: J Ethnopharmacol Year: 2013 Type: Article

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