Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease.

Sharma, Kumar; Karl, Bethany; Mathew, Anna V; Gangoiti, Jon A; Wassel, Christina L; Saito, Rintaro; Pu, Minya; Sharma, Shoba; You, Young-Hyun; Wang, Lin; Diamond-Stanic, Maggie; Lindenmeyer, Maja T; Forsblom, Carol; Wu, Wei; Ix, Joachim H; Ideker, Trey; Kopp, Jeffrey B; Nigam, Sanjay K; Cohen, Clemens D; Groop, Per-Henrik; Barshop, Bruce A; Natarajan, Loki; Nyhan, William L; Naviaux, Robert K

Sharma, Kumar; Karl, Bethany; Mathew, Anna V; Gangoiti, Jon A; Wassel, Christina L; Saito, Rintaro; Pu, Minya; Sharma, Shoba; You, Young-Hyun; Wang, Lin; Diamond-Stanic, Maggie; Lindenmeyer, Maja T; Forsblom, Carol; Wu, Wei; Ix, Joachim H; Ideker, Trey; Kopp, Jeffrey B; Nigam, Sanjay K; Cohen, Clemens D; Groop, Per-Henrik; Barshop, Bruce A; Natarajan, Loki; Nyhan, William L; Naviaux, Robert K.

Affiliation

Sharma K; Institute of Metabolomic Medicine.

J Am Soc Nephrol ; 24(11): 1901-12, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23949796

Subject(s)

Diabetic Nephropathies/metabolism; Metabolomics/methods; Mitochondrial Diseases/etiology; Adult; Aged; Female; Glomerular Filtration Rate; Humans; Ion Transport; Male; Middle Aged; Organic Anion Transport Protein 1/genetics; Organic Anion Transporters, Sodium-Independent/genetics; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Renal Insufficiency, Chronic/metabolism; Transcription Factors/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondrial Diseases / Diabetic Nephropathies / Metabolomics Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Am Soc Nephrol Journal subject: NEFROLOGIA Year: 2013 Type: Article

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