Cyclodextrin-based microcapsules as bioreactors for ATP biosynthesis.

Li, Jian-Hu; Wang, Yi-Fu; Ha, Wei; Liu, Yan; Ding, Li-Sheng; Li, Bang-Jing; Zhang, Sheng

Li, Jian-Hu; Wang, Yi-Fu; Ha, Wei; Liu, Yan; Ding, Li-Sheng; Li, Bang-Jing; Zhang, Sheng.

Affiliation

Li JH; State Key Laboratory of Polymer Materials Engineering, Polymer Research Institute of Sichuan University, Chengdu 610065, China.

Biomacromolecules ; 14(9): 2984-8, 2013 Sep 09.

Article in En | MEDLINE | ID: mdl-23962233

ABSTRACT

ABSTRACT

A biomimetic energy converter was fabricated via the assembly of CF0F1-ATPase on lipid-coated hollow nanocapsules composed of α-cyclodextrins/chitosan-graft-poly(ethylene glycol) methacrylate. Upon entrapped GOD into these capsules, the addition of glucose could trigger proton-motive force and then drive the rotation of ATPase to synthesize ATP.

Subject(s)

Adenosine Triphosphate/biosynthesis; Cyclodextrins/chemistry; Mitochondrial Proton-Translocating ATPases/chemistry; Nanocapsules/chemistry; Biocatalysis; Bioreactors; Chitosan/analogs & derivatives; Chitosan/chemistry; Glucose/chemistry; Glucose Oxidase/chemistry; Hydrogen-Ion Concentration; Kinetics; Lipids/chemistry; Particle Size; Polyethylene Glycols/chemistry; Polymethacrylic Acids/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenosine Triphosphate / Cyclodextrins / Mitochondrial Proton-Translocating ATPases / Nanocapsules Language: En Journal: Biomacromolecules Journal subject: BIOLOGIA MOLECULAR Year: 2013 Type: Article Affiliation country: China

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