Preventive and therapeutic effects of adenanthin on experimental autoimmune encephalomyelitis by inhibiting NF-&#954;B signaling.

Yin, Qian-Qian; Liu, Chuan-Xu; Wu, Ying-Li; Wu, Shao-Fang; Wang, Yan; Zhang, Xia; Hu, Xiao-Juan; Pu, Jian-Xin; Lu, Ying; Zhou, Hu-Chen; Wang, Hong-Lin; Nie, Hong; Sun, Han-Dong; Chen, Guo-Qiang

Preventive and therapeutic effects of adenanthin on experimental autoimmune encephalomyelitis by inhibiting NF-κB signaling.

Yin, Qian-Qian; Liu, Chuan-Xu; Wu, Ying-Li; Wu, Shao-Fang; Wang, Yan; Zhang, Xia; Hu, Xiao-Juan; Pu, Jian-Xin; Lu, Ying; Zhou, Hu-Chen; Wang, Hong-Lin; Nie, Hong; Sun, Han-Dong; Chen, Guo-Qiang.

Affiliation

Yin QQ; Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

J Immunol ; 191(5): 2115-25, 2013 Sep 01.

Article in En | MEDLINE | ID: mdl-23964105

Subject(s)

Diterpenes/pharmacology; Encephalomyelitis, Autoimmune, Experimental/metabolism; NF-kappa B/metabolism; Signal Transduction/drug effects; Animals; Blotting, Western; Electrophoretic Mobility Shift Assay; Encephalomyelitis, Autoimmune, Experimental/immunology; Flow Cytometry; Immunohistochemistry; Lymphocyte Activation/drug effects; Lymphocyte Activation/immunology; Male; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes/drug effects; T-Lymphocytes/immunology; T-Lymphocytes/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / NF-kappa B / Diterpenes / Encephalomyelitis, Autoimmune, Experimental Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunol Year: 2013 Type: Article Affiliation country: China

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