Regulated norepinephrine transporter interaction with the neurokinin-1 receptor establishes transporter subcellular localization.

Arapulisamy, Obulakshmi; Mannangatti, Padmanabhan; Jayanthi, Lankupalle D

Arapulisamy, Obulakshmi; Mannangatti, Padmanabhan; Jayanthi, Lankupalle D.

Affiliation

Arapulisamy O; From the Department of Neurosciences, Division of Neuroscience Research, Medical University of South Carolina, Charleston, South Carolina 29425 and.

J Biol Chem ; 288(40): 28599-610, 2013 Oct 04.

Article in En | MEDLINE | ID: mdl-23979140

Subject(s)

Norepinephrine Plasma Membrane Transport Proteins/metabolism; Receptors, Neurokinin-1/metabolism; Animals; Down-Regulation/drug effects; Endocytosis/drug effects; Humans; Male; Membrane Microdomains/drug effects; Membrane Microdomains/metabolism; Norepinephrine/metabolism; Peptide Fragments/pharmacology; Protein Binding/drug effects; Protein Transport/drug effects; Rats; Rats, Sprague-Dawley; Subcellular Fractions/drug effects; Subcellular Fractions/metabolism; Substance P/analogs & derivatives; Substance P/pharmacology

Key words

Catecholamines; G Protein-coupled Receptors (GPCR); Internalization; Lipid Rafts; Monoamine Transporters; Plasma Membrane; Protein-protein Interactions; Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Neurokinin-1 / Norepinephrine Plasma Membrane Transport Proteins Limits: Animals / Humans / Male Language: En Journal: J Biol Chem Year: 2013 Type: Article

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