Feeding soy protein isolate and treatment with estradiol have different effects on mammary gland morphology and gene expression in weanling male and female rats.

Miousse, Isabelle R; Sharma, Neha; Blackburn, Michael; Vantrease, Jamie; Gomez-Acevedo, Horacio; Hennings, Leah; Shankar, Kartik; Cleves, Mario A; Badger, Thomas M; Ronis, Martin J J

Miousse, Isabelle R; Sharma, Neha; Blackburn, Michael; Vantrease, Jamie; Gomez-Acevedo, Horacio; Hennings, Leah; Shankar, Kartik; Cleves, Mario A; Badger, Thomas M; Ronis, Martin J J.

Affiliation

Miousse IR; Arkansas Children's Nutrition Center, Little Rock Arkansas;

Physiol Genomics ; 45(22): 1072-83, 2013 Nov 15.

Article in En | MEDLINE | ID: mdl-24046281

Subject(s)

Estradiol/pharmacology; Estrogens/pharmacology; Mammary Glands, Animal/drug effects; Soybean Proteins/pharmacology; Animals; Cell Differentiation/drug effects; Cell Proliferation/drug effects; Down-Regulation; Estrogen Receptor alpha/genetics; Estrogen Receptor alpha/metabolism; Estrogen Receptor beta/genetics; Estrogen Receptor beta/metabolism; Female; Gene Expression; Male; Mammary Glands, Animal/cytology; Mammary Glands, Animal/growth & development; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Sex Factors; Weaning

Key words

17ß-estradiol; chromatin immunoprecipitation; mammary gland; microarray; soy; xenoestrogen

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Soybean Proteins / Estradiol / Estrogens / Mammary Glands, Animal Limits: Animals Language: En Journal: Physiol Genomics Journal subject: BIOLOGIA MOLECULAR Year: 2013 Type: Article

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