Pyrithiamine-induced thiamine deficiency alters proliferation and neurogenesis in both neurogenic and vulnerable areas of the rat brain.

Hazell, Alan S; Wang, Dongmei; Oanea, Raluca; Sun, Simon; Aghourian, Meghmik; Yong, Jee Jung

Hazell, Alan S; Wang, Dongmei; Oanea, Raluca; Sun, Simon; Aghourian, Meghmik; Yong, Jee Jung.

Metab Brain Dis ; 29(1): 145-52, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24078061

Subject(s)

Brain/drug effects; Neurogenesis/drug effects; Pyrithiamine/toxicity; Wernicke Encephalopathy/pathology; Animals; Brain/pathology; Cell Division/drug effects; Cells, Cultured; DNA Replication/drug effects; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Hippocampus/drug effects; Hippocampus/pathology; Inferior Colliculi/drug effects; Inferior Colliculi/pathology; Lateral Ventricles/drug effects; Lateral Ventricles/pathology; Male; Microtubule-Associated Proteins/analysis; Neural Stem Cells/drug effects; Neural Stem Cells/pathology; Neuropeptides/analysis; Rats; Rats, Sprague-Dawley; Thalamus/drug effects; Thalamus/pathology; Wernicke Encephalopathy/chemically induced

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Collection: 01-internacional Database: MEDLINE Main subject: Pyrithiamine / Wernicke Encephalopathy / Brain / Neurogenesis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Metab Brain Dis Journal subject: CEREBRO / METABOLISMO Year: 2014 Type: Article

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