Tumor cell heterogeneity.

Chekhun, V F; Sherban, S D; Savtsova, Z D

Chekhun, V F; Sherban, S D; Savtsova, Z D.

Affiliation

Chekhun VF; R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine, Kyiv 03022, Ukraine.

Exp Oncol ; 35(3): 154-62, 2013 Sep.

Article in En | MEDLINE | ID: mdl-24084451

ABSTRACT

ABSTRACT

The paper deals with the analysis of literary data on the tumor cell heterogeneity. Phenotypic, genetic and epigenetic mechanisms of heterogeneity are considered. The heterogeneity of metastasis is considered too. The importance for the biology of populations of tumor cells and the sensitivity of tumors to therapeutic treatment are discussed.

Subject(s)

Neoplasms/genetics; Neoplasms/pathology; Animals; Humans; Phenotype

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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Neoplasms Limits: Animals / Humans Language: En Journal: Exp Oncol Journal subject: NEOPLASIAS Year: 2013 Type: Article Affiliation country: Ukraine

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