Immune evasion by pathogenic Leptospira strains: the secretion of proteases that directly cleave complement proteins.

Fraga, Tatiana Rodrigues; Courrol, Daniella Dos Santos; Castiblanco-Valencia, Mónica Marcela; Hirata, Izaura Yoshico; Vasconcellos, Sílvio Arruda; Juliano, Luiz; Barbosa, Angela Silva; Isaac, Lourdes

Fraga, Tatiana Rodrigues; Courrol, Daniella Dos Santos; Castiblanco-Valencia, Mónica Marcela; Hirata, Izaura Yoshico; Vasconcellos, Sílvio Arruda; Juliano, Luiz; Barbosa, Angela Silva; Isaac, Lourdes.

Affiliation

Fraga TR; Department of Immunology, Institute of Biomedical Sciences.

J Infect Dis ; 209(6): 876-86, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24163418

Subject(s)

Bacterial Proteins/metabolism; Complement C3/metabolism; Leptospira/immunology; Leptospirosis/microbiology; Peptide Hydrolases/metabolism; Bacterial Proteins/chemistry; Bacterial Proteins/isolation & purification; Complement Pathway, Classical; Humans; Immune Evasion; Leptospira/chemistry; Leptospira/enzymology; Leptospira/pathogenicity; Leptospirosis/immunology; Models, Biological; Peptide Hydrolases/immunology; Peptide Hydrolases/isolation & purification; Recombinant Proteins/chemistry; Recombinant Proteins/metabolism; Thermolysin/chemistry; Thermolysin/metabolism

Key words

Complement System; Immune Evasion; Innate Immunity; Leptospira; Leptospirosis; Proteases

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Hydrolases / Bacterial Proteins / Complement C3 / Leptospira / Leptospirosis Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Infect Dis Year: 2014 Type: Article

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