Antibiotic resistance genes in the bacteriophage DNA fraction of human fecal samples.
Antimicrob Agents Chemother
; 58(1): 606-9, 2014.
Article
in En
| MEDLINE
| ID: mdl-24165177
ABSTRACT
A group of antibiotic resistance genes (ARGs) (blaTEM, blaCTX-M-1, mecA, armA, qnrA, and qnrS) were analyzed by real-time quantitative PCR (qPCR) in bacteriophage DNA isolated from feces from 80 healthy humans. Seventy-seven percent of the samples were positive in phage DNA for one or more ARGs. blaTEM, qnrA, and, blaCTX-M-1 were the most abundant, and armA, qnrS, and mecA were less prevalent. Free bacteriophages carrying ARGs may contribute to the mobilization of ARGs in intra- and extraintestinal environments.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bacteriophages
/
Drug Resistance, Microbial
/
Anti-Bacterial Agents
Limits:
Humans
Language:
En
Journal:
Antimicrob Agents Chemother
Year:
2014
Type:
Article
Affiliation country:
Spain