Spectroscopic elucidation of the inhibitory mechanism of Cys2His2 zinc finger transcription factors by cobalt(III) Schiff base complexes.

Heffern, Marie C; Kurutz, Josh W; Meade, Thomas J

Heffern, Marie C; Kurutz, Josh W; Meade, Thomas J.

Affiliation

Heffern MC; Department of Chemistry, Molecular Biosciences, Neurobiology, Biomedical Engineering, and Radiology, Northwestern University, Evanston, Illinois 60208-3113 (USA).

Chemistry ; 19(50): 17043-53, 2013 Dec 09.

Article in En | MEDLINE | ID: mdl-24203451

Subject(s)

Cobalt/chemistry; Cobalt/pharmacology; Coordination Complexes/chemistry; Coordination Complexes/pharmacology; Cystine/chemistry; Histidine/chemistry; Metalloproteins/chemistry; Oligopeptides/chemistry; Schiff Bases/chemistry; Schiff Bases/pharmacology; Transcription Factors/chemistry; Binding Sites; Ligands; Magnetic Resonance Spectroscopy; Protein Structure, Secondary; Zinc Fingers

Key words

Schiff bases; cobalt; spectroscopy; transcription factors; zinc fingers

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Schiff Bases / Transcription Factors / Cobalt / Cystine / Coordination Complexes / Histidine / Metalloproteins Type of study: Prognostic_studies Language: En Journal: Chemistry Journal subject: QUIMICA Year: 2013 Type: Article

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