Role of glucuronidation for hepatic detoxification and urinary elimination of toxic bile acids during biliary obstruction.

Perreault, Martin; Bialek, Andrzej; Trottier, Jocelyn; Verreault, Mélanie; Caron, Patrick; Milkiewicz, Piotr; Barbier, Olivier

Perreault, Martin; Bialek, Andrzej; Trottier, Jocelyn; Verreault, Mélanie; Caron, Patrick; Milkiewicz, Piotr; Barbier, Olivier.

Affiliation

Perreault M; Laboratory of molecular pharmacology, CHU-Québec Research Centre and the Faculty of Pharmacy, Laval University, Québec, Canada.

PLoS One ; 8(11): e80994, 2013.

Article in En | MEDLINE | ID: mdl-24244729

Subject(s)

Bile Acids and Salts/toxicity; Bile Acids and Salts/urine; Cholestasis/metabolism; Cholestasis/urine; Liver/metabolism; Apoptosis/drug effects; Chenodeoxycholic Acid/toxicity; Chenodeoxycholic Acid/urine; Deoxycholic Acid/toxicity; Deoxycholic Acid/urine; Female; Hep G2 Cells; Humans; Lithocholic Acid/toxicity; Lithocholic Acid/urine; Male

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bile Acids and Salts / Cholestasis / Liver Limits: Female / Humans / Male Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Type: Article Affiliation country: Canada

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