A model-driven quantitative metabolomics analysis of aerobic and anaerobic metabolism in E. coli K-12 MG1655 that is biochemically and thermodynamically consistent.

McCloskey, Douglas; Gangoiti, Jon A; King, Zachary A; Naviaux, Robert K; Barshop, Bruce A; Palsson, Bernhard O; Feist, Adam M

McCloskey, Douglas; Gangoiti, Jon A; King, Zachary A; Naviaux, Robert K; Barshop, Bruce A; Palsson, Bernhard O; Feist, Adam M.

Affiliation

McCloskey D; Department of Bioengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, California, 92093-0412.

Biotechnol Bioeng ; 111(4): 803-15, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24249002

Subject(s)

Escherichia coli/metabolism; Metabolomics/methods; Models, Biological; Aerobiosis/physiology; Anaerobiosis/physiology; Bioengineering; Bioreactors/microbiology; Metabolic Networks and Pathways/physiology; Thermodynamics

Key words

anaerobic/aerobic E. coli; constraint-based analysis; genome-scale modeling; metabolomics; thermodynamics analysis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Escherichia coli / Metabolomics / Models, Biological Language: En Journal: Biotechnol Bioeng Year: 2014 Type: Article

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