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Effects of vinpocetine and ozagrel on behavioral recovery of rats after global brain ischemia.
Jincai, Wang; Tingfang, Dong; Yongheng, Zhang; Zhongmin, Lu; Kaihua, Zhai; Xiaohong, Liu.
Affiliation
  • Jincai W; The First Affiliated Hospital of Xinxiang Medical University, No. 88 Jiankang Road, Weihui 453100, Henan Province, China.
  • Tingfang D; The First Affiliated Hospital of Xinxiang Medical University, No. 88 Jiankang Road, Weihui 453100, Henan Province, China. Electronic address: tingfang_dong@163.com.
  • Yongheng Z; The First Affiliated Hospital of Xinxiang Medical University, No. 88 Jiankang Road, Weihui 453100, Henan Province, China.
  • Zhongmin L; The First Affiliated Hospital of Xinxiang Medical University, No. 88 Jiankang Road, Weihui 453100, Henan Province, China.
  • Kaihua Z; The First Affiliated Hospital of Xinxiang Medical University, No. 88 Jiankang Road, Weihui 453100, Henan Province, China.
  • Xiaohong L; The First Affiliated Hospital of Xinxiang Medical University, No. 88 Jiankang Road, Weihui 453100, Henan Province, China.
J Clin Neurosci ; 21(4): 661-3, 2014 Apr.
Article in En | MEDLINE | ID: mdl-24291485
ABSTRACT
Brain ischemia leads to severe disruption of the nervous system and recovery is often prolonged. Rehabilitative post-ischemia pharmacological treatment may therefore be important for behavioral recovery, especially for cognition and motor behavior. The present study investigated the effects of combined vinpocetine and ozagrel administration on the behavioral recovery of rats from global brain ischemia. The results suggest that the combined treatment leads to significantly better improvement compared to single drug administration. We conclude that the combined use of vinpocetine and ozagrel may provide beneficial effects to patients suffering from brain ischemia.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vinca Alkaloids / Brain Ischemia / Neuroprotective Agents / Maze Learning / CA1 Region, Hippocampal / Methacrylates Limits: Animals Language: En Journal: J Clin Neurosci Journal subject: NEUROLOGIA Year: 2014 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vinca Alkaloids / Brain Ischemia / Neuroprotective Agents / Maze Learning / CA1 Region, Hippocampal / Methacrylates Limits: Animals Language: En Journal: J Clin Neurosci Journal subject: NEUROLOGIA Year: 2014 Type: Article Affiliation country: China