Transgenic mice expressing mutant Pinin exhibit muscular dystrophy, nebulin deficiency and elevated expression of slow-type muscle fiber genes.

Wu, Hsu-Pin; Hsu, Shu-Yuan; Wu, Wen-Ai; Hu, Ji-Wei; Ouyang, Pin

Wu, Hsu-Pin; Hsu, Shu-Yuan; Wu, Wen-Ai; Hu, Ji-Wei; Ouyang, Pin.

Affiliation

Wu HP; Department of Anatomy, Chang Gung University Medical College, Taiwan.
Hsu SY; Department of Anatomy, Chang Gung University Medical College, Taiwan.
Wu WA; Transgenic Mouse Core Laboratory, Chang Gung University, Taiwan.
Hu JW; Transgenic Mouse Core Laboratory, Chang Gung University, Taiwan.
Ouyang P; Department of Anatomy, Chang Gung University Medical College, Taiwan; Transgenic Mouse Core Laboratory, Chang Gung University, Taiwan; Molecular Medicine Research Center, Chang Gung University, Taiwan. Electronic address: ouyang@mail.cgu.edu.tw.

Biochem Biophys Res Commun ; 443(1): 313-20, 2014 Jan 03.

Article in En | MEDLINE | ID: mdl-24309110

Subject(s)

Cell Adhesion Molecules/genetics; Gene Expression Regulation; Muscle Fibers, Slow-Twitch/metabolism; Muscle Proteins/deficiency; Muscular Dystrophies/genetics; Muscular Dystrophies/metabolism; Nuclear Proteins/genetics; Animals; Cell Adhesion Molecules/chemistry; DNA-Binding Proteins; Drosophila Proteins/genetics; Gene Expression Profiling; HeLa Cells; Humans; Mice; Mice, Transgenic; Nuclear Proteins/chemistry; Protein Structure, Tertiary

Key words

Muscular dystrophy; Nebulin; Pinin; Slow type fiber gene

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Cell Adhesion Molecules / Gene Expression Regulation / Muscle Fibers, Slow-Twitch / Muscle Proteins / Muscular Dystrophies Limits: Animals / Humans Language: En Journal: Biochem Biophys Res Commun Year: 2014 Type: Article Affiliation country: Taiwan

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