CO(2) laser versus cold steel margin analysis following endoscopic excision of glottic cancer.
J Otolaryngol Head Neck Surg
; 43: 6, 2014 Feb 06.
Article
in En
| MEDLINE
| ID: mdl-24502856
ABSTRACT
OBJECTIVE:
To compare the suitability of CO2 laser with steel instruments for margin excision in transoral laser microsurgery.METHODS:
Prospective randomized blinded study. Patients with glottic cancer undergoing laser resection were randomized to margin excision by either steel instruments or CO2 laser. Margins were analyzed for size, interpretability and degree of artifact by a pathologist who was blinded to technique.RESULTS:
45 patients were enrolled in the study with 226 total margins taken. 39 margins taken by laser had marked artifact and 0 were uninterpretable. 20 margins taken by steel instruments had marked artifact, and 2 were uninterpretable. Controlling for margin size, the laser technique was associated with increasing degrees of margin artifact (p = 0.210), but there was no difference in crude rates of uninterpretability (p = 0.24).CONCLUSION:
Laser margin excision is associated with a greater degree of artifact than steel instrument excision, but was not associated with higher rate of uninterpretability.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Precancerous Conditions
/
Steel
/
Surgical Instruments
/
Carcinoma, Squamous Cell
/
Laryngeal Neoplasms
/
Lasers, Gas
/
Laryngoscopy
/
Larynx
/
Microsurgery
Type of study:
Clinical_trials
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Otolaryngol Head Neck Surg
Journal subject:
OTORRINOLARINGOLOGIA
Year:
2014
Type:
Article