Vaccination with the RSV fusion protein formulated with a combination adjuvant induces long-lasting protective immunity.

Garg, R; Latimer, L; Gerdts, V; Potter, A; van Drunen Littel-van den Hurk, S

Garg, R; Latimer, L; Gerdts, V; Potter, A; van Drunen Littel-van den Hurk, S.

Affiliation

Garg R; VIDO-Intervac, University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada.
Latimer L; VIDO-Intervac, University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada.
Gerdts V; VIDO-Intervac, University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada.
Potter A; Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada.
van Drunen Littel-van den Hurk S; VIDO-Intervac, University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada.

J Gen Virol ; 95(Pt 5): 1043-1054, 2014 May.

Article in En | MEDLINE | ID: mdl-24572813

Subject(s)

Adjuvants, Immunologic/administration & dosage; Respiratory Syncytial Virus Vaccines/immunology; Respiratory Syncytial Viruses/immunology; Vaccination/methods; Viral Fusion Proteins/immunology; Animals; Antibodies, Viral/analysis; Antibodies, Viral/blood; Cytokines/immunology; Female; Immunoglobulin A/analysis; Immunoglobulin G/blood; Leukocytes, Mononuclear/immunology; Longitudinal Studies; Lung/immunology; Mice; Mice, Inbred BALB C; Oligodeoxyribonucleotides/administration & dosage; Poly I-C/administration & dosage; Respiratory Syncytial Virus Vaccines/administration & dosage; Spleen/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Syncytial Viruses / Viral Fusion Proteins / Adjuvants, Immunologic / Vaccination / Respiratory Syncytial Virus Vaccines Type of study: Observational_studies Limits: Animals Language: En Journal: J Gen Virol Year: 2014 Type: Article Affiliation country: Canada

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