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In vivo methods for drug absorption - comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects.
Sjögren, Erik; Abrahamsson, Bertil; Augustijns, Patrick; Becker, Dieter; Bolger, Michael B; Brewster, Marcus; Brouwers, Joachim; Flanagan, Talia; Harwood, Matthew; Heinen, Christian; Holm, René; Juretschke, Hans-Paul; Kubbinga, Marlies; Lindahl, Anders; Lukacova, Viera; Münster, Uwe; Neuhoff, Sibylle; Nguyen, Mai Anh; Peer, Achiel van; Reppas, Christos; Hodjegan, Amin Rostami; Tannergren, Christer; Weitschies, Werner; Wilson, Clive; Zane, Patricia; Lennernäs, Hans; Langguth, Peter.
Affiliation
  • Sjögren E; Department of Pharmacy, Uppsala University, Uppsala, Sweden.
  • Abrahamsson B; AstraZeneca R&D, Mölndal, Sweden.
  • Augustijns P; Drug Delivery and Disposition, KU Leuven, Leuven, Belgium.
  • Becker D; Vivo Drug Delivery GmbH, Wollerau, Switzerland.
  • Bolger MB; Simulations Plus Inc., Lancaster, CA, USA.
  • Brewster M; Janssen Research and Development, Beerse, Belgium.
  • Brouwers J; Drug Delivery and Disposition, KU Leuven, Leuven, Belgium.
  • Flanagan T; AstraZeneca R&D, Macclesfield, UK.
  • Harwood M; Simcyp Ltd., Sheffield, UK.
  • Heinen C; Institute of Pharmacy and Biochemistry, Johannes Gutenberg University Mainz, Mainz, Germany.
  • Holm R; H. Lundbeck A/S, Valby, Denmark.
  • Juretschke HP; Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany.
  • Kubbinga M; Institute of Pharmacy and Biochemistry, Johannes Gutenberg University Mainz, Mainz, Germany; National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
  • Lindahl A; Medical Products Agency, Uppsala, Sweden.
  • Lukacova V; Simulations Plus Inc., Lancaster, CA, USA.
  • Münster U; Bayer Pharma AG, Wuppertal, Germany.
  • Neuhoff S; Simcyp Ltd., Sheffield, UK.
  • Nguyen MA; Institute of Pharmacy and Biochemistry, Johannes Gutenberg University Mainz, Mainz, Germany.
  • Peer Av; Janssen Research and Development, Beerse, Belgium.
  • Reppas C; Faculty of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece.
  • Hodjegan AR; University of Manchester, Manchester, UK.
  • Tannergren C; AstraZeneca R&D, Mölndal, Sweden.
  • Weitschies W; Center of Drug Absorption and Transport, University of Greifswald, Greifswald, Germany.
  • Wilson C; University of Strathclyde, Glasgow, UK.
  • Zane P; Sanofi US, Bridgewater, NJ, USA.
  • Lennernäs H; Department of Pharmacy, Uppsala University, Uppsala, Sweden.
  • Langguth P; Institute of Pharmacy and Biochemistry, Johannes Gutenberg University Mainz, Mainz, Germany. Electronic address: langguth@uni-mainz.de.
Eur J Pharm Sci ; 57: 99-151, 2014 Jun 16.
Article in En | MEDLINE | ID: mdl-24637348
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biopharmaceutics / Pharmacokinetics / Pharmaceutical Preparations / Food-Drug Interactions / Gastrointestinal Tract / Excipients / Intestinal Absorption Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Eur J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2014 Type: Article Affiliation country: Sweden
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biopharmaceutics / Pharmacokinetics / Pharmaceutical Preparations / Food-Drug Interactions / Gastrointestinal Tract / Excipients / Intestinal Absorption Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Eur J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2014 Type: Article Affiliation country: Sweden