Evidence for an angiotensin-(1-7) neuropeptidase expressed in the brain medulla and CSF of sheep.

Marshall, Allyson C; Pirro, Nancy T; Rose, James C; Diz, Debra I; Chappell, Mark C

Marshall, Allyson C; Pirro, Nancy T; Rose, James C; Diz, Debra I; Chappell, Mark C.

Affiliation

Marshall AC; Hypertension and Vascular Research Center, Wake Forest School of Medicine, Winston Salem, North Carolina, USA.

J Neurochem ; 130(2): 313-23, 2014 Jul.

Article in En | MEDLINE | ID: mdl-24661079

Subject(s)

Angiotensin I/biosynthesis; Angiotensin I/cerebrospinal fluid; Medulla Oblongata/enzymology; Peptide Fragments/biosynthesis; Peptide Fragments/cerebrospinal fluid; Peptidyl-Dipeptidase A/biosynthesis; Peptidyl-Dipeptidase A/cerebrospinal fluid; Animals; Bradykinin/metabolism; Chromatography, Agarose; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; In Vitro Techniques; Intercellular Signaling Peptides and Proteins/metabolism; Kinetics; Mercury Compounds/pharmacology; Neurotensin/metabolism; Oligopeptides/pharmacology; Protease Inhibitors/pharmacology; Sheep; Substrate Specificity

Key words

Ang-(1-7); Renin-angiotensin system; metabolism; neuropeptidase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Angiotensin I / Medulla Oblongata / Peptidyl-Dipeptidase A Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Neurochem Year: 2014 Type: Article Affiliation country: United States

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