Expression of human CD46 modulates inflammation associated with GalTKO lung xenograft injury.

Burdorf, L; Stoddard, T; Zhang, T; Rybak, E; Riner, A; Avon, C; Laaris, A; Cheng, X; Sievert, E; Braileanu, G; Newton, A; Phelps, C J; Ayares, D; Azimzadeh, A M; Pierson, R N

Burdorf, L; Stoddard, T; Zhang, T; Rybak, E; Riner, A; Avon, C; Laaris, A; Cheng, X; Sievert, E; Braileanu, G; Newton, A; Phelps, C J; Ayares, D; Azimzadeh, A M; Pierson, R N.

Affiliation

Burdorf L; Division of Cardiac Surgery, Department of Surgery, University of Maryland School of Medicine, and VA Maryland Health Care System, Baltimore, MD.

Am J Transplant ; 14(5): 1084-95, 2014 May.

Article in En | MEDLINE | ID: mdl-24698431

Subject(s)

CD55 Antigens/genetics; Galactosyltransferases/physiology; Graft Survival/physiology; Inflammation/pathology; Lung Injury/immunology; Lung Transplantation; Animals; Animals, Genetically Modified; Blood Coagulation/immunology; Complement Activation/immunology; Epitopes/immunology; Histamine/metabolism; Humans; Immunoenzyme Techniques; Inflammation/immunology; Inflammation/metabolism; Lung Injury/pathology; Lung Injury/surgery; Neutrophils/metabolism; Swine; Swine, Miniature; Transplantation, Heterologous

Key words

Coagulation; GalTKO.hCD46; complement; ex vivo perfusion; leukocyte adhesion; lung; platelet activation; xenotransplantation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lung Transplantation / CD55 Antigens / Lung Injury / Galactosyltransferases / Graft Survival / Inflammation Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Am J Transplant Journal subject: TRANSPLANTE Year: 2014 Type: Article Affiliation country: Moldova

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