In vivo molecular imaging of cathepsin and matrix metalloproteinase activity discriminates between arthritic and osteoarthritic processes in mice.

Vermeij, Eline A; Koenders, Marije I; Blom, Arjen B; Arntz, Onno J; Bennink, Miranda B; van den Berg, Wim B; van Lent, Peter L E M; van de Loo, Fons A J

Vermeij, Eline A; Koenders, Marije I; Blom, Arjen B; Arntz, Onno J; Bennink, Miranda B; van den Berg, Wim B; van Lent, Peter L E M; van de Loo, Fons A J.

Mol Imaging ; 13: 1-10, 2014.

Article in En | MEDLINE | ID: mdl-24881106

Subject(s)

Arthritis, Rheumatoid/metabolism; Cathepsins/analysis; Matrix Metalloproteinases/analysis; Molecular Imaging/methods; Osteoarthritis/metabolism; Animals; Arthritis, Experimental/metabolism; Cathepsins/metabolism; Cell Death; Chondrocytes/cytology; Chondrocytes/metabolism; Collagen Type II/adverse effects; Collagen Type II/immunology; Male; Matrix Metalloproteinases/metabolism; Mice; Mice, Inbred C57BL; Stifle/chemistry; Stifle/metabolism; Stifle/pathology

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Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Arthritis, Rheumatoid / Cathepsins / Matrix Metalloproteinases / Molecular Imaging Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Imaging Journal subject: DIAGNOSTICO POR IMAGEM Year: 2014 Type: Article

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