Synthesis and biological activity of Schiff base series of valproyl, N-valproyl glycinyl, and N-valproyl-4-aminobenzoyl hydrazide derivatives.

El-Faham, Ayman; Farooq, Muhammad; Khattab, Sherine Nabil; Elkayal, Ahmed Mohamed; Ibrahim, Mahmoud Fawzy; Abutaha, Nael; Wadaan, Mohammad Ahmad; Hamed, Ezzat Awad

El-Faham, Ayman; Farooq, Muhammad; Khattab, Sherine Nabil; Elkayal, Ahmed Mohamed; Ibrahim, Mahmoud Fawzy; Abutaha, Nael; Wadaan, Mohammad Ahmad; Hamed, Ezzat Awad.

Affiliation

El-Faham A; Department of Chemistry, College of Science, King Saud University.

Chem Pharm Bull (Tokyo) ; 62(6): 591-9, 2014.

Article in En | MEDLINE | ID: mdl-24881666

Subject(s)

Angiogenesis Inhibitors/pharmacology; Antineoplastic Agents/pharmacology; Hydrazines/pharmacology; Neovascularization, Physiologic/drug effects; Schiff Bases/pharmacology; Valproic Acid/pharmacology; Angiogenesis Inhibitors/chemical synthesis; Angiogenesis Inhibitors/chemistry; Animals; Antineoplastic Agents/chemical synthesis; Antineoplastic Agents/chemistry; Cell Proliferation/drug effects; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Hydrazines/chemical synthesis; Hydrazines/chemistry; Molecular Structure; Schiff Bases/chemical synthesis; Schiff Bases/chemistry; Structure-Activity Relationship; Valproic Acid/analogs & derivatives; Valproic Acid/chemical synthesis; Zebrafish

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Collection: 01-internacional Database: MEDLINE Main subject: Schiff Bases / Valproic Acid / Neovascularization, Physiologic / Angiogenesis Inhibitors / Hydrazines / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Chem Pharm Bull (Tokyo) Year: 2014 Type: Article

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