2-(Hetero(aryl)methylene)hydrazine-1-carbothioamides as potent urease inhibitors.

Saeed, Aamer; Imran, Aqeel; Channar, Pervaiz A; Shahid, Mohammad; Mahmood, Wajahat; Iqbal, Jamshed

Saeed, Aamer; Imran, Aqeel; Channar, Pervaiz A; Shahid, Mohammad; Mahmood, Wajahat; Iqbal, Jamshed.

Affiliation

Saeed A; Department of Chemistry, Quaid-I-Azam University, Islamabad, 45320, Pakistan.

Chem Biol Drug Des ; 85(2): 225-30, 2015 Feb.

Article in En | MEDLINE | ID: mdl-24938644

Subject(s)

Canavalia/enzymology; Enzyme Inhibitors/chemistry; Hydrazines/chemistry; Thioamides/chemistry; Urease/antagonists & inhibitors; Enzyme Inhibitors/pharmacology; Hydrazines/pharmacology; Models, Molecular; Structure-Activity Relationship; Thioamides/pharmacology; Urease/metabolism

Key words

Schiff bases; molecular modeling; thiosemicarbazones; urease inhibitors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thioamides / Urease / Canavalia / Enzyme Inhibitors / Hydrazines Type of study: Prognostic_studies Language: En Journal: Chem Biol Drug Des Journal subject: BIOQUIMICA / FARMACIA / FARMACOLOGIA Year: 2015 Type: Article Affiliation country: Pakistan

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