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Determinants of PCR performance (Xpert MTB/RIF), including bacterial load and inhibition, for TB diagnosis using specimens from different body compartments.
Theron, Grant; Peter, Jonny; Calligaro, Greg; Meldau, Richard; Hanrahan, Colleen; Khalfey, Hoosain; Matinyenya, Brian; Muchinga, Tapuwa; Smith, Liezel; Pandie, Shaheen; Lenders, Laura; Patel, Vinod; Mayosi, Bongani M; Dheda, Keertan.
Affiliation
  • Theron G; Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Peter J; Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Calligaro G; Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Meldau R; Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Hanrahan C; Johns Hopkins Bloomberg School of Public Health, Department of Epidemiology, Baltimore, MD, USA.
  • Khalfey H; Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Matinyenya B; Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Muchinga T; Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Smith L; Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Pandie S; Division of Cardiology, Department of Medicine, Groote Schuur Hospital and University of Cape Town, South Africa.
  • Lenders L; Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa.
  • Patel V; Department of Neurology, University of KwaZulu Natal, South Africa.
  • Mayosi BM; Division of Cardiology, Department of Medicine, Groote Schuur Hospital and University of Cape Town, South Africa.
  • Dheda K; 1] Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa [2] Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Sci Rep ; 4: 5658, 2014 Jul 11.
Article in En | MEDLINE | ID: mdl-25014250
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / HIV Infections / Bacterial Load / Real-Time Polymerase Chain Reaction / Antibiotics, Antitubercular / Mycobacterium tuberculosis Type of study: Diagnostic_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Africa Language: En Journal: Sci Rep Year: 2014 Type: Article Affiliation country: South Africa
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / HIV Infections / Bacterial Load / Real-Time Polymerase Chain Reaction / Antibiotics, Antitubercular / Mycobacterium tuberculosis Type of study: Diagnostic_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Africa Language: En Journal: Sci Rep Year: 2014 Type: Article Affiliation country: South Africa