Induction of epithelial-mesenchymal transition and loss of podoplanin expression are associated with progression of lymph node metastases in human papillomavirus-related oropharyngeal carcinoma.

Wakisaka, Naohiro; Yoshida, Shinya; Kondo, Satoru; Kita, Makiko; Sawada-Kitamura, Seiko; Endo, Kazuhira; Tsuji, Akira; Nakanish, Yosuke; Murono, Shigeyuki; Yoshizaki, Tomokazu

Wakisaka, Naohiro; Yoshida, Shinya; Kondo, Satoru; Kita, Makiko; Sawada-Kitamura, Seiko; Endo, Kazuhira; Tsuji, Akira; Nakanish, Yosuke; Murono, Shigeyuki; Yoshizaki, Tomokazu.

Affiliation

Wakisaka N; Division of Otolaryngology-Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.

Histopathology ; 66(6): 771-80, 2015 May.

Article in En | MEDLINE | ID: mdl-25039283

Subject(s)

Carcinoma, Squamous Cell/pathology; Carcinoma, Squamous Cell/virology; Epithelial-Mesenchymal Transition; Head and Neck Neoplasms/pathology; Head and Neck Neoplasms/virology; Oropharyngeal Neoplasms/pathology; Oropharyngeal Neoplasms/virology; Papillomavirus Infections/complications; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor/analysis; Carcinoma, Squamous Cell/mortality; Disease Progression; Female; Head and Neck Neoplasms/mortality; Humans; Immunohistochemistry; Lymphatic Metastasis/pathology; Male; Membrane Glycoproteins/biosynthesis; Middle Aged; Oropharyngeal Neoplasms/mortality; Squamous Cell Carcinoma of Head and Neck

Key words

epithelial-mesenchymal transition; human papillomavirus; lymph node metastasis; oropharyngeal cancer; podoplanin

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Oropharyngeal Neoplasms / Papillomavirus Infections / Epithelial-Mesenchymal Transition / Head and Neck Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Histopathology Year: 2015 Type: Article Affiliation country: Japan

Fulltext

XML

PubMed Links

Search on Google