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'Click' assembly of glycoclusters and discovery of a trehalose analogue that retards Aß40 aggregation and inhibits Aß40-induced neurotoxicity.
Rajaram, Hemalatha; Palanivelu, Manoj Kumar; Arumugam, Thiruma V; Rao, Venkatesan M; Shaw, P Nicholas; McGeary, Ross P; Ross, Benjamin P.
Affiliation
  • Rajaram H; The University of Queensland, School of Pharmacy, Brisbane, Queensland 4072, Australia.
  • Palanivelu MK; The University of Queensland, School of Pharmacy, Brisbane, Queensland 4072, Australia.
  • Arumugam TV; Department of Physiology, Yong Loo Lin School Medicine, National University of Singapore, Singapore 117597, Singapore.
  • Rao VM; The University of Queensland, School of Pharmacy, Brisbane, Queensland 4072, Australia.
  • Shaw PN; The University of Queensland, School of Pharmacy, Brisbane, Queensland 4072, Australia.
  • McGeary RP; The University of Queensland, School of Chemistry and Molecular Biosciences, Brisbane, Queensland 4072, Australia.
  • Ross BP; The University of Queensland, School of Pharmacy, Brisbane, Queensland 4072, Australia. Electronic address: b.ross1@uq.edu.au.
Bioorg Med Chem Lett ; 24(18): 4523-4528, 2014 Sep 15.
Article in En | MEDLINE | ID: mdl-25172417
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Trehalose / Glycoconjugates / Amyloid beta-Peptides / Neuroprotective Agents / Drug Discovery / Click Chemistry / Neurons Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article Affiliation country: Australia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Trehalose / Glycoconjugates / Amyloid beta-Peptides / Neuroprotective Agents / Drug Discovery / Click Chemistry / Neurons Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article Affiliation country: Australia