Blood typing profile of a school-aged population of a North Togo township.
Hemoglobin
; 38(5): 316-8, 2014.
Article
in En
| MEDLINE
| ID: mdl-25271992
ABSTRACT
The aim of this study was the determination of hemoglobin (Hb) variants and ABO blood groups in a school population aged 6 to 9 years in the township of Agbandé-Yaka in North Togo. A cross-sectional study was carried out on 570 children of four primary schools at Agbande-Yaka, between March and July 2010. Hemoglobin characterization was done by alkaline buffer electrophoresis and the blood types ABO-Rhesus (Rh) D by immuno-hematological methods. A Hb variant was detected in 37.0% of the schoolchildren. Among them, the AS trait accounted for 11.9% and the AC trait for 20.2%. Homozygous Hb S (HBB c.20A>T) was not found but Hb C (HBB c.19G>A) appeared at a frequency of 3.3%, while compound heterozygotes carrying Hb SC were seen at a frequency of 1.6%. The O, B and A blood groups accounted for 49.0, 26.8 and 21.9%, respectively. The Hb anomalies reached a high prevalence in this school population. These results are remarkable by the absence of homozygous Hb S individuals compared to homozygous Hb C individuals, which were as numerous as expected. The frequencies of the ABO blood groups are similar to what has been found in other West African populations.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rh-Hr Blood-Group System
/
ABO Blood-Group System
/
Hemoglobin C
/
Hemoglobin, Sickle
/
Polymorphism, Single Nucleotide
/
Hemoglobin C Disease
/
Hemoglobin SC Disease
Type of study:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limits:
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
Africa
Language:
En
Journal:
Hemoglobin
Year:
2014
Type:
Article
Affiliation country:
Togo