Asymmetric synthesis of (-)-brevipolide H through cyclopropanation of the &#945;,ß-unsaturated ketone.

Lin, Jing-Wen; Kurniawan, Yudhi Dwi; Chang, Wen-Jung; Leu, Wohn-Jenn; Chan, She-Hung; Hou, Duen-Ren

Asymmetric synthesis of (-)-brevipolide H through cyclopropanation of the α,ß-unsaturated ketone.

Lin, Jing-Wen; Kurniawan, Yudhi Dwi; Chang, Wen-Jung; Leu, Wohn-Jenn; Chan, She-Hung; Hou, Duen-Ren.

Affiliation

Lin JW; Department of Chemistry, National Central University , No. 300 Jhong-Da Road, Jhong-li, Taoyuan, Taiwan 32001.

Org Lett ; 16(20): 5328-31, 2014 Oct 17.

Article in En | MEDLINE | ID: mdl-25275479

Subject(s)

Antineoplastic Agents/chemical synthesis; CCR5 Receptor Antagonists/chemical synthesis; Cyclopropanes/chemical synthesis; Ketones/chemistry; Pyrones/chemical synthesis; Antineoplastic Agents/chemistry; Antineoplastic Agents/pharmacology; CCR5 Receptor Antagonists/chemistry; CCR5 Receptor Antagonists/pharmacology; Cyclopropanes/chemistry; Cyclopropanes/pharmacology; Humans; Hyptis/chemistry; Inhibitory Concentration 50; Ketones/chemical synthesis; Molecular Structure; Pyrones/chemistry; Pyrones/pharmacology; Stereoisomerism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrones / Cyclopropanes / CCR5 Receptor Antagonists / Ketones / Antineoplastic Agents Limits: Humans Language: En Journal: Org Lett Journal subject: BIOQUIMICA Year: 2014 Type: Article

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