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Perforin competent CD8 T cells are sufficient to cause immune-mediated blood-brain barrier disruption.
Johnson, Holly L; Willenbring, Robin C; Jin, Fang; Manhart, Whitney A; LaFrance, Stephanie J; Pirko, Istvan; Johnson, Aaron J.
Affiliation
  • Johnson HL; Department of Neurology, Mayo Clinic, Rochester, Minnesota, United States of America; Department of Immunology, Mayo Clinic, Rochester, Minnesota, United States of America; Neurobiology of Disease Graduate Program, Mayo Graduate School, Rochester, Minnesota, United States of America.
  • Willenbring RC; Department of Immunology, Mayo Clinic, Rochester, Minnesota, United States of America; Virology and Gene Therapy Graduate Program, Mayo Graduate School, Rochester, Minnesota, United States of America.
  • Jin F; Department of Immunology, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Manhart WA; Department of Immunology, Mayo Clinic, Rochester, Minnesota, United States of America.
  • LaFrance SJ; Department of Immunology, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Pirko I; Department of Neurology, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Johnson AJ; Department of Neurology, Mayo Clinic, Rochester, Minnesota, United States of America; Department of Immunology, Mayo Clinic, Rochester, Minnesota, United States of America.
PLoS One ; 9(10): e111401, 2014.
Article in En | MEDLINE | ID: mdl-25337791
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood-Brain Barrier / CD8-Positive T-Lymphocytes / Perforin Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2014 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood-Brain Barrier / CD8-Positive T-Lymphocytes / Perforin Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2014 Type: Article Affiliation country: United States