Isolation of pyrrolocins A-C: cis- and trans-decalin tetramic acid antibiotics from an endophytic fungal-derived pathway.

Jadulco, Raquel C; Koch, Michael; Kakule, Thomas B; Schmidt, Eric W; Orendt, Anita; He, Haiyin; Janso, Jeffrey E; Carter, Guy T; Larson, Erica C; Pond, Christopher; Matainaho, Teatulohi K; Barrows, Louis R

Jadulco, Raquel C; Koch, Michael; Kakule, Thomas B; Schmidt, Eric W; Orendt, Anita; He, Haiyin; Janso, Jeffrey E; Carter, Guy T; Larson, Erica C; Pond, Christopher; Matainaho, Teatulohi K; Barrows, Louis R.

Affiliation

Jadulco RC; Department of Pharmacology and Toxicology, Department of Medicinal Chemistry, and ΔCenter for High Performance Computing, University of Utah , Salt Lake City, Utah United States.

J Nat Prod ; 77(11): 2537-44, 2014 Nov 26.

Article in En | MEDLINE | ID: mdl-25351193

Subject(s)

Anti-Bacterial Agents/isolation & purification; Anti-Bacterial Agents/pharmacology; Endophytes/chemistry; Ferns/microbiology; Pyrrolidinones/isolation & purification; Pyrrolidinones/pharmacology; Anti-Bacterial Agents/chemistry; Bacillus subtilis/drug effects; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis/drug effects; Naphthalenes/chemistry; Nuclear Magnetic Resonance, Biomolecular; Papua New Guinea; Pyrrolidinones/chemistry; Staphylococcus aureus/drug effects; Stereoisomerism; Streptococcus pneumoniae/drug effects; Tetrahydronaphthalenes/chemistry

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidinones / Ferns / Endophytes / Anti-Bacterial Agents Language: En Journal: J Nat Prod Year: 2014 Type: Article

Fulltext

XML

PubMed Links

Search on Google