Cancer stem cell-like phenotype and survival are coordinately regulated by Akt/FoxO/Bim pathway.

Gargini, Ricardo; Cerliani, Juan P; Escoll, Maribel; Antón, Inés M; Wandosell, Francisco

Gargini, Ricardo; Cerliani, Juan P; Escoll, Maribel; Antón, Inés M; Wandosell, Francisco.

Affiliation

Gargini R; Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), C/Nicolas Cabrera 1, Universidad Autonoma Madrid, Madrid, Spain; Centro Nacional de Biotecnología (CNB-CSIC), C/Darwin 3, Madrid, Spain; 3Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), C/Valderrebollo 5, Madrid, Spain.

Stem Cells ; 33(3): 646-60, 2015 Mar.

Article in En | MEDLINE | ID: mdl-25407338

Subject(s)

Apoptosis Regulatory Proteins/metabolism; Breast Neoplasms/metabolism; Breast Neoplasms/pathology; Forkhead Transcription Factors/metabolism; Membrane Proteins/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Proto-Oncogene Proteins/metabolism; Apoptosis; Bcl-2-Like Protein 11; Cell Line, Tumor; Cell Proliferation/physiology; Female; Forkhead Box Protein O1; Humans; MCF-7 Cells; Phenotype; Signal Transduction

Key words

Apoptosis; Breast cancer; Cancer stem cells; Cell signaling; Signal transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Proto-Oncogene Proteins / Proto-Oncogene Proteins c-akt / Apoptosis Regulatory Proteins / Forkhead Transcription Factors / Membrane Proteins Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Stem Cells Year: 2015 Type: Article Affiliation country: Spain

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