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Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways.
Pratheeshkumar, Poyil; Son, Young-Ok; Divya, Sasidharan Padmaja; Roy, Ram Vinod; Hitron, John Andrew; Wang, Lei; Kim, Donghern; Dai, Jin; Asha, Padmaja; Zhang, Zhuo; Wang, Yitao; Shi, Xianglin.
Affiliation
  • Pratheeshkumar P; Center for Research on Environmental Disease, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA; Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA.
  • Son YO; Center for Research on Environmental Disease, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA; Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA.
  • Divya SP; Center for Research on Environmental Disease, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA; Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA.
  • Roy RV; Center for Research on Environmental Disease, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA; Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA.
  • Hitron JA; Center for Research on Environmental Disease, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA; Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA.
  • Wang L; Center for Research on Environmental Disease, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA; Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA.
  • Kim D; Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA.
  • Dai J; Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA.
  • Asha P; National Centre for Aquatic Animal Health, Cochin University of Science and Technology, Cochin, India.
  • Zhang Z; Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA.
  • Wang Y; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, China.
  • Shi X; Center for Research on Environmental Disease, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA; Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536, USA. Electronic address: xshi5@email.uky.edu.
Toxicol Appl Pharmacol ; 281(2): 230-41, 2014 Dec 01.
Article in En | MEDLINE | ID: mdl-25448439
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Potassium Dichromate / Bronchi / Signal Transduction / Cell Transformation, Neoplastic / Free Radical Scavengers / Chromium / Anticarcinogenic Agents / Reactive Oxygen Species / Oxidative Stress / Luteolin Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Toxicol Appl Pharmacol Year: 2014 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Potassium Dichromate / Bronchi / Signal Transduction / Cell Transformation, Neoplastic / Free Radical Scavengers / Chromium / Anticarcinogenic Agents / Reactive Oxygen Species / Oxidative Stress / Luteolin Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Toxicol Appl Pharmacol Year: 2014 Type: Article Affiliation country: United States